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The Mtr4 ratchet helix and arch domain both function to promote RNA unwinding

Mtr4 is a conserved Ski2-like RNA helicase and a subunit of the TRAMP complex that activates exosome-mediated 3′-5′ turnover in nuclear RNA surveillance and processing pathways. Prominent features of the Mtr4 structure include a four-domain ring-like helicase core and a large arch domain that spans...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Taylor, Lacy L., Jackson, Ryan N., Rexhepaj, Megi, King, Alejandra Klauer, Lott, Lindsey K., van Hoof, Ambro, Johnson, Sean J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267639/
https://ncbi.nlm.nih.gov/pubmed/25414331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1208
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