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The crystal structure of Mtr4 reveals a novel arch domain required for rRNA processing

The essential RNA helicase, Mtr4, performs a critical role in RNA processing and degradation as an activator of the nuclear exosome. The molecular basis for this vital function is not understood and detailed analysis is significantly limited by the lack of structural data. In this study, we present...

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Sonraí Bibleagrafaíochta
Main Authors: Jackson, Ryan N, Klauer, A Alejandra, Hintze, Bradley J, Robinson, Howard, van Hoof, Ambro, Johnson, Sean J
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2010
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905245/
https://ncbi.nlm.nih.gov/pubmed/20512111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.107
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