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Citrullinated Histone H3 – A Novel Target for Treatment of Sepsis
INTRODUCTION: We have recently demonstrated that in a rodent model of lipopolysaccharide (LPS)-induced shock, an increase in circulating citrullinated histone H3 (Cit H3) is associated with lethality of sepsis, and treatment with suberoylanilide hydroxamic acid (SAHA), a histone deacetylase (HDAC) i...
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| Udgivet i: | Surgery |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267527/ https://ncbi.nlm.nih.gov/pubmed/24957671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2014.04.009 |
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