MACROD2 overexpression mediates estrogen independent growth and tamoxifen resistance in breast cancers

Tamoxifen is effective for treating estrogen receptor-alpha (ER) positive breast cancers. However, few molecular mediators of tamoxifen resistance have been elucidated. Here we describe a previously unidentified gene, MACROD2 that confers tamoxifen resistance and estrogen independent growth. We foun...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Mohseni, Morassa, Cidado, Justin, Croessmann, Sarah, Cravero, Karen, Cimino-Mathews, Ashley, Wong, Hong Yuen, Scharpf, Rob, Zabransky, Daniel J., Abukhdeir, Abde M., Garay, Joseph P., Wang, Grace M., Beaver, Julia A., Cochran, Rory L., Blair, Brian G., Rosen, D. Marc, Erlanger, Bracha, Argani, Pedram, Hurley, Paula J., Lauring, Josh, Park, Ben Ho
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267353/
https://ncbi.nlm.nih.gov/pubmed/25422431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408650111
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items