Gain-of-function CCR4 mutations in adult T cell leukemia/lymphoma

Adult T cell leukemia/lymphoma (ATLL) is an aggressive malignancy caused by human T cell lymphotropic virus type-I (HTLV-I) without curative treatment at present. To illuminate the pathogenesis of ATLL we performed whole transcriptome sequencing of purified ATLL patient samples and discovered recurr...

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Publicat a:J Exp Med
Autors principals: Nakagawa, Masao, Schmitz, Roland, Xiao, Wenming, Goldman, Carolyn K., Xu, Weihong, Yang, Yandan, Yu, Xin, Waldmann, Thomas A., Staudt, Louis M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2014
Matèries:
Brief Definitive Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267233/
https://ncbi.nlm.nih.gov/pubmed/25488980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20140987
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