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Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

The Trypanosomatidae family, composed of unicellular parasites, causes severe vector-borne diseases that afflict human populations worldwide. Chagas disease, sleeping sickness, as well as different sorts of leishmaniases are amongst the most important infectious diseases produced by Trypanosoma cruz...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Balaña-Fouce, Rafael, Álvarez-Velilla, Raquel, Fernández-Prada, Christopher, García-Estrada, Carlos, Reguera, Rosa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266802/
https://ncbi.nlm.nih.gov/pubmed/25516844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2014.07.006
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