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Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?
Drug discovery programs sponsored by public or private initiatives pursue the same ambitious goal: a crushing defeat of major Neglected Tropical Diseases (NTDs) during this decade. Both target-based and target-free screenings have pros and cons when it comes to finding potential small-molecule leads...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2014-12-01
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Colecção: | International Journal for Parasitology: Drugs and Drug Resistance |
Assuntos: | |
Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S2211320714000098 |
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