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Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?

Drug discovery programs sponsored by public or private initiatives pursue the same ambitious goal: a crushing defeat of major Neglected Tropical Diseases (NTDs) during this decade. Both target-based and target-free screenings have pros and cons when it comes to finding potential small-molecule leads...

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Hlavní autoři: Rosa M. Reguera, Estefanía Calvo-Álvarez, Raquel Álvarez-Velilla, Rafael Balaña-Fouce
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2014-12-01
Edice:International Journal for Parasitology: Drugs and Drug Resistance
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S2211320714000098
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