Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?

Por Rosa M. Reguera, Estefanía Calvo-Álvarez, Raquel Álvarez-Velilla, Rafael Balaña-Fouce
Publicado em 2014-12-01

Deletion study of DNA topoisomerase IB from Leishmania donovani: searching for a minimal functional heterodimer.

Por Rosario Díaz González, Yolanda Pérez Pertejo, David Ordóñez, Rafael Balaña-Fouce, Rosa M Reguera
Publicado em 2007-01-01

Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery

Por Rafael Balaña-Fouce, Raquel Álvarez-Velilla, Christopher Fernández-Prada, Carlos García-Estrada, Rosa M. Reguera
Publicado em 2014-12-01

Antileishmanial activity of terpenylquinones on Leishmania infantum and their effects on Leishmania topoisomerase IB

Por Yolanda Pérez-Pertejo, José M. Escudero-Martínez, Rosa M. Reguera, Rafael Balaña-Fouce, Pablo A. García, Pablo G. Jambrina, Arturo San Feliciano, María-Ángeles Castro
Publicado em 2019-12-01