Progression-Free Survival Remains Poor Over Sequential Lines of Systemic Therapy in Patients with BRAF-mutated Colorectal Cancer

BACKGROUND: BRAF mutations occur in 5–10% of metastatic colorectal cancers and are biomarkers associated with a poor prognosis. However, the outcomes with standard chemotherapy over sequential lines of therapy in a large cohort of patients with BRAF-mutant tumors have not been described. METHODS: We...

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Foilsithe in:Clin Colorectal Cancer
Main Authors: Morris, Van K., Overman, Michael J., Jiang, Zhi-Qin, Garrett, Chris, Agarwal, Shweta, Eng, Cathy, Kee, Bryan, Fogelman, David, Dasari, Arvind, Wolff, Robert, Maru, Dipen, Kopetz, Scott
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266576/
https://ncbi.nlm.nih.gov/pubmed/25069797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clcc.2014.06.001
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