IODINE MONOCHLORIDE FACILITATED DEGLYCOSYLATION, ANOMERIZATION, AND ISOMERIZATION OF 3-SUBSTITUTED THYMIDINE ANALOGUES

The reaction of thymidine, 3-mono-, and 3,3′,5′-trialkylsubstitued thymidine analogues with iodine monochloride (ICl) was investigated. Treatment with ICl resulted in rapid deglycosylation, anomerization, and isomerization of thymidine and 3-substituted thymidine analogues under various reaction con...

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Gepubliceerd in:Nucleosides Nucleotides Nucleic Acids
Hoofdauteurs: Khalil, Ahmed, Ishita, Keisuke, Ali, Tehane, Tiwari, Rohit, Riachy, Ramy, Toppino, Antonio, Hasabelnaby, Sherifa, Sayfullin, Naum, Oliver, Allen G., Gallucci, Judith, Huang, Zhenguo, Tjarks, Werner
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4266569/
https://ncbi.nlm.nih.gov/pubmed/25372994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15257770.2014.945648
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