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N3-substituted thymidine bioconjugates for cancer therapy and imaging

The compound class of 3-carboranyl thymidine analogues (3CTAs) are boron delivery agents for boron neutron capture therapy (BNCT), a binary treatment modality for cancer. Presumably, these compounds accumulate selectively in tumor cells via intracellular trapping, which is mediated by hTK1. Favorabl...

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Detalhes bibliográficos
Main Authors: Khalil, Ahmed, Ishita, Keisuke, Ali, Tehane, Tjarks, Werner
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816973/
https://ncbi.nlm.nih.gov/pubmed/23617430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.13.31
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