CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain

The multi-domain CX3CL1 transmembrane chemokine triggers leukocyte adherence without rolling and migration by presenting its chemokine domain (CD) to its receptor CX3CR1. Through the combination of functional adhesion assays with structural analysis using FRAP, we investigated the functional role of...

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Dettagli Bibliografici
Pubblicato in:Biol Open
Autori principali: Ostuni, Mariano A., Guellec, Julie, Hermand, Patricia, Durand, Pauline, Combadière, Christophe, Pincet, Frédéric, Deterre, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265755/
https://ncbi.nlm.nih.gov/pubmed/25395671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20149845
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