CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain

The multi-domain CX3CL1 transmembrane chemokine triggers leukocyte adherence without rolling and migration by presenting its chemokine domain (CD) to its receptor CX3CR1. Through the combination of functional adhesion assays with structural analysis using FRAP, we investigated the functional role of...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Ostuni, Mariano A., Guellec, Julie, Hermand, Patricia, Durand, Pauline, Combadière, Christophe, Pincet, Frédéric, Deterre, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265755/
https://ncbi.nlm.nih.gov/pubmed/25395671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20149845
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