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CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain

The multi-domain CX3CL1 transmembrane chemokine triggers leukocyte adherence without rolling and migration by presenting its chemokine domain (CD) to its receptor CX3CR1. Through the combination of functional adhesion assays with structural analysis using FRAP, we investigated the functional role of...

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Dades bibliogràfiques
Publicat a:Biol Open
Autors principals: Ostuni, Mariano A., Guellec, Julie, Hermand, Patricia, Durand, Pauline, Combadière, Christophe, Pincet, Frédéric, Deterre, Philippe
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4265755/
https://ncbi.nlm.nih.gov/pubmed/25395671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20149845
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