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The scaffold protein WRAP53β orchestrates the ubiquitin response critical for DNA double-strand break repair
The WD40 domain-containing protein WRAP53β (WD40 encoding RNA antisense to p53; also referred to as WDR79/TCAB1) controls trafficking of splicing factors and the telomerase enzyme to Cajal bodies, and its functional loss has been linked to carcinogenesis, premature aging, and neurodegeneration. Here...
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| Vydáno v: | Genes Dev |
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| Hlavní autoři: | , , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4265676/ https://ncbi.nlm.nih.gov/pubmed/25512560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.246546.114 |
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