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Splicing controls the ubiquitin response during DNA double-strand break repair
Although evidence that splicing regulates DNA repair is accumulating, the underlying mechanism(s) remain unclear. Here, we report that short-term inhibition of pre-mRNA splicing by spliceosomal inhibitors impairs cellular repair of DNA double-strand breaks. Indeed, interference with splicing as litt...
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| Izdano u: | Cell Death Differ |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5041194/ https://ncbi.nlm.nih.gov/pubmed/27315300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.58 |
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