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The Making of a Sweet Modification: Structure and Function of O-GlcNAc Transferase

O-GlcNAc transferase is an essential mammalian enzyme responsible for transferring a single GlcNAc moiety from UDP-GlcNAc to specific serine/threonine residues of hundreds of nuclear and cytoplasmic proteins. This modification is dynamic and has been implicated in numerous signaling pathways. An une...

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Publicado en:J Biol Chem
Autores principales: Janetzko, John, Walker, Suzanne
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263849/
https://ncbi.nlm.nih.gov/pubmed/25336649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.604405
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