Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

The human T-cell leukemia virus type I Tax protein trans-activates several cellular genes implicated in T-cell replication and activation. To investigate its leukemogenic potential, Tax was targeted to the mature T-lymphocyte compartment in transgenic mice by using the human granzyme B promoter. The...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Grossman, W J, Kimata, J T, Wong, F H, Zutter, M, Ley, T J, Ratner, L
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.4.1057
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