Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.
The human T-cell leukemia virus type I Tax protein trans-activates several cellular genes implicated in T-cell replication and activation. To investigate its leukemogenic potential, Tax was targeted to the mature T-lymphocyte compartment in transgenic mice by using the human granzyme B promoter. The...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1995
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42636/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7862633/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.4.1057 |
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