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Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast
Embryonic (ES) and trophoblast (TS) stem cells reflect the first, irrevocable cell fate decision in development that is reinforced by distinct epigenetic lineage barriers. Nonetheless, ES cells can seemingly acquire TS-like characteristics upon manipulation of lineage-determining transcription facto...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Pub. Group
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263130/ https://ncbi.nlm.nih.gov/pubmed/25423963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6538 |
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