Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5

Mouse ES cells can differentiate into all three germ layers of the embryo but are generally excluded from the trophoblast lineage. Here we show that ES cells deficient in DNA methylation can differentiate efficiently into trophoblast derivatives. In a genome-wide screen we identify the transcription...

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Detaylı Bibliyografya
Asıl Yazarlar: Ng, Ray Kit, Dean, Wendy, Dawson, Claire, Lucifero, Diana, Madeja, Zofia, Reik, Wolf, Hemberger, Myriam
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635539/
https://ncbi.nlm.nih.gov/pubmed/18836439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb1786
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