Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.
DNA methylation patterns are reprogrammed in primordial germ cells and in preimplantation embryos by demethylation and subsequent de novo methylation. It has been suggested that epigenetic reprogramming may be necessary for the embryonic genome to return to a pluripotent state. We have carried out a...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science (PLoS)
2008-06-01
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| シリーズ: | PLoS Genetics |
| オンライン･アクセス: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000116&type=printable |
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