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RAF translocations expand cancer targets
Chromosomal translocations can promote cancers by eliciting the expression of fusion genes with oncogenic activity. The identification of translocations affecting RAF genes in prostate and gastric cancers and melanoma provides compelling evidence for the key role of RAF signaling in a subset of thes...
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| Publicado en: | Nat Med |
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| Autor Principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263025/ https://ncbi.nlm.nih.gov/pubmed/20613748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm0710-749 |
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