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Emerging Concepts in the Analysis of Transcriptional Targets of the MYC Oncoprotein: Are the Targets Targetable?

Activation of the MYC oncoprotein is among the most ubiquitous events in human cancer. MYC functions in part as a sequence-specific regulator of transcription. Although early searches for direct downstream target genes that explain MYC’s potent biological activity were met with enthusiasm, the postg...

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Detalhes bibliográficos
Autor principal: McMahon, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083113/
https://ncbi.nlm.nih.gov/pubmed/21533016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910379011
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