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Senescence of human fibroblasts induced by oncogenic Raf

The oncogenes RAS and RAF came to view as agents of neoplastic transformation. However, in normal cells, these genes can have effects that run counter to oncogenic transformation, such as arrest of the cell division cycle, induction of cell differentiation, and apoptosis. Recent work has demonstrate...

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Publicat a:Genes Dev
Autors principals: Zhu, Jiyue, Woods, Douglas, McMahon, Martin, Bishop, J. Michael
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.19.2997
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