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Senescence of human fibroblasts induced by oncogenic Raf

The oncogenes RAS and RAF came to view as agents of neoplastic transformation. However, in normal cells, these genes can have effects that run counter to oncogenic transformation, such as arrest of the cell division cycle, induction of cell differentiation, and apoptosis. Recent work has demonstrate...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Genes Dev
Principais autores: Zhu, Jiyue, Woods, Douglas, McMahon, Martin, Bishop, J. Michael
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1998
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC317194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765202/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.19.2997
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