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The α7 nicotinic receptor agonist ABT-107 protects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions

The finding that smoking is inversely correlated with Parkinson's disease and that nicotine attenuates nigrostriatal damage in parkinsonian animals supports the idea that nicotine may be neuroprotective. Nicotine is thought to exert this effect by acting at nicotinic receptors (nAChRs), includi...

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Detalles Bibliográficos
Publicado en:Exp Neurol
Main Authors: Bordia, Tanuja, McGregor, Matthew, Papke, Roger L., Decker, Michael W., McIntosh, J. Michael, Quik, Maryka
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262739/
https://ncbi.nlm.nih.gov/pubmed/25261754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.09.015
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