Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys

Nicotine reduces dopaminergic deficits in parkinsonian animals when administered before nigrostriatal damage. Here we tested whether nicotine is also beneficial when given to rats and monkeys with pre-existing nigrostriatal damage. Rats were administered nicotine before and after a unilateral 6-hydr...

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Hauptverfasser: Huang, Luping Z., Parameswaran, Neeraja, Bordia, Tanuja, McIntosh, J. Michael, Quik, Maryka
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677631/
https://ncbi.nlm.nih.gov/pubmed/19250334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06011.x
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