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VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors
Liver microenvironment is a critical determinant for development and progression of liver metastasis. Under TGF-β stimulation, hepatic stellate cells (HSCs), which are liver specific pericytes, transdifferentiate into tumor associated myofibroblasts that promote tumor implantation and growth in the...
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| Опубликовано в: : | Hepatology |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4262723/ https://ncbi.nlm.nih.gov/pubmed/24917558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27251 |
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