VASP promotes TGF-β activation of hepatic stellate cells by regulating Rab11 dependent plasma membrane targeting of TGF-β receptors

Liver microenvironment is a critical determinant for development and progression of liver metastasis. Under TGF-β stimulation, hepatic stellate cells (HSCs), which are liver specific pericytes, transdifferentiate into tumor associated myofibroblasts that promote tumor implantation and growth in the...

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Publicado en:Hepatology
Main Authors: Tu, Kangsheng, Li, Jiachu, Verma, Vikas K, Liu, Chunsheng, Billadeau, Daniel D., Lamprecht, Georg, Xiang, Xiaoyu, Guo, Luyang, Dhanasekaran, Renumathy, Roberts, Lewis R., Shah, Vijay H., Kang, Ningling
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262723/
https://ncbi.nlm.nih.gov/pubmed/24917558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27251
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