A High Fat Diet and NAD(+) Rescue Premature Aging in Cockayne Syndrome

Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in the genes encoding the DNA repair proteins CSA or CSB. Csb(m/m) mice were given a high fat, caloric restricted or resveratrol supplemented diet. The high fat diet rescued the...

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Publicado no:Cell Metab
Main Authors: Scheibye-Knudsen, Morten, Mitchell, Sarah J., Fang, Evandro F., Iyama, Teruaki, Ward, Theresa, Wang, James, Dunn, Christopher A., Singh, Nagendra, Veith, Sebastian, Hasan, M. Mahdi, Mangerich, Aswin, Wilson, Mark A., Mattson, Mark P., Bergersen, Linda H., Cogger, Victoria C., Warren, Alessandra, Le Couteur, David G., Moaddel, Ruin, Wilson, David M., Croteau, Deborah L., de Cabo, Rafael, Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261735/
https://ncbi.nlm.nih.gov/pubmed/25440059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.10.005
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