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Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling
Cockayne syndrome (CS) is a rare premature aging disease, most commonly caused by mutations of the genes encoding the CSA or CSB proteins. CS patients display cachectic dwarfism and severe neurological manifestations and have an average life expectancy of 12 years. The CS proteins are involved in tr...
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| Опубликовано в: : | Aging Cell |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2020
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7744955/ https://ncbi.nlm.nih.gov/pubmed/33166073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13268 |
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