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Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling

Cockayne syndrome (CS) is a rare premature aging disease, most commonly caused by mutations of the genes encoding the CSA or CSB proteins. CS patients display cachectic dwarfism and severe neurological manifestations and have an average life expectancy of 12 years. The CS proteins are involved in tr...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Okur, Mustafa N., Fang, Evandro F., Fivenson, Elayne M., Tiwari, Vinod, Croteau, Deborah L., Bohr, Vilhelm A.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744955/
https://ncbi.nlm.nih.gov/pubmed/33166073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13268
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