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Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD(+) signaling

Cockayne syndrome (CS) is a rare premature aging disease, most commonly caused by mutations of the genes encoding the CSA or CSB proteins. CS patients display cachectic dwarfism and severe neurological manifestations and have an average life expectancy of 12 years. The CS proteins are involved in tr...

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Bibliografski detalji
Izdano u:Aging Cell
Glavni autori: Okur, Mustafa N., Fang, Evandro F., Fivenson, Elayne M., Tiwari, Vinod, Croteau, Deborah L., Bohr, Vilhelm A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7744955/
https://ncbi.nlm.nih.gov/pubmed/33166073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13268
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