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Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons.

Mutation in superoxide dismutase 1 (SOD1), a Cu/Zn enzyme that removes oxygen radicals and protects against oxidative injury, has been implicated in some cases of familial amyotrophic lateral sclerosis (FALS). As a first approach to examining the mechanism(s) through which these mutations cause spec...

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Autores principales: Pardo, C A, Xu, Z, Borchelt, D R, Price, D L, Sisodia, S S, Cleveland, D W
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC42615/
https://ncbi.nlm.nih.gov/pubmed/7862672
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