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Mutant Cu,Zn superoxide dismutase in motor neuron disease

Cu,Zn superoxide dismutase (Cu,Zn SOD) is one of several anti-oxidant enzymes which defend the cell against damage by oxygen free radicals. Mutations of the SOD1 gene encoding Cu,Zn SOD are found familial amyotrophic lateral sclerosis, a progressive and fatal paralytic disease which is caused by the...

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Bibliographic Details
Main Authors: Gurney, Mark E., Liu, Rugao, Althaus, John S., Hall, Edward D., Becker, David A.
Format: Artigo
Language:Inglês
Published: Kluwer Academic Publishers 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455714/
https://ncbi.nlm.nih.gov/pubmed/23604357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-998-0012-x
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