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The protective effect of growth hormone on Cu/Zn superoxide dismutase-mutant motor neurons
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is characterized by selective degeneration of motor neurons. The gene encoding Cu/Zn superoxide dismutase (SOD1) is responsible for 20% of familial ALS cases. Growth hormone (GH) concentrations are low in the cerebrospinal fluid of patients with ALS; h...
Shranjeno v:
izdano v: | BMC Neurosci |
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Main Authors: | , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
BioMed Central
2015
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4326297/ https://ncbi.nlm.nih.gov/pubmed/25655275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-015-0140-z |
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