Protective effect of neurofilament heavy gene overexpression in motor neuron disease induced by mutant superoxide dismutase

To investigate the role of neurofilaments in motor neuron disease caused by superoxide dismutase (SOD1) mutations, transgenic mice expressing a amyotrophic lateral sclerosis-linked SOD1 mutant (SOD1(G37R)) were mated with transgenic mice expressing human neurofilament heavy (NF-H) subunits. Unexpect...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Couillard-Després, Sébastien, Zhu, Qinzhang, Wong, Philip C., Price, Donald L., Cleveland, Don W., Julien, Jean-Pierre
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21389/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9689131/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.16.9626
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