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Reduction of axonal caliber does not alleviate motor neuron disease caused by mutant superoxide dismutase 1

It is well established that motor neurons with large axon caliber are selectively affected in amyotrophic lateral sclerosis (ALS). To investigate whether high neurofilament (NF) content and large axonal caliber are factors that predispose motor neurons to selective degeneration in ALS, we generated...

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Detalhes bibliográficos
Main Authors: Nguyen, Minh Dang, Larivière, Roxanne C., Julien, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17337/
https://ncbi.nlm.nih.gov/pubmed/11050249
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