A single point mutation leading to loss of catalytic activity in human thiopurine S-methyltransferase.

Thiopurine S-methyltransferase (TPMT; S-adenosyl-L-methionine:thiopurine S-methyltransferase, EC 2.1.1.67) activity exhibits genetic polymorphism, with approximately 0.33% of Caucasians and African-Americans inheriting TPMT deficiency as an autosomal recessive trait. To determine the molecular genet...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Krynetski, E Y, Schuetz, J D, Galpin, A J, Pui, C H, Relling, M V, Evans, W E
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1995
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC42614/
https://ncbi.nlm.nih.gov/pubmed/7862671
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia