Periostin is required for maximal airways inflammation and hyperresponsiveness in mice

BACKGROUND: Periostin, a secreted extracellular matrix protein, has been localized to deposits of subepithelial fibrosis in asthma, and periostin levels have been linked to elevation of IL-13. OBJECTIVE: We hypothesized that periostin is required for airway inflammatory responses to a physiologic ae...

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Gepubliceerd in:J Allergy Clin Immunol
Hoofdauteurs: Bentley, J. Kelley, Chen, Qiang, Hong, Jun Young, Popova, Antonia P., Lei, Jing, Moore, Bethany B., Hershenson, Marc B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261024/
https://ncbi.nlm.nih.gov/pubmed/24996263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.05.029
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