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Periostin is required for maximal airways inflammation and hyperresponsiveness in mice
BACKGROUND: Periostin, a secreted extracellular matrix protein, has been localized to deposits of subepithelial fibrosis in asthma, and periostin levels have been linked to elevation of IL-13. OBJECTIVE: We hypothesized that periostin is required for airway inflammatory responses to a physiologic ae...
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| Publicat a: | J Allergy Clin Immunol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4261024/ https://ncbi.nlm.nih.gov/pubmed/24996263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2014.05.029 |
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