Enterovirus D68 infection induces IL-17–dependent neutrophilic airway inflammation and hyperresponsiveness

Enterovirus D68 (EV-D68) shares biologic features with rhinovirus (RV). In 2014, a nationwide outbreak of EV-D68 was associated with severe asthma-like symptoms. We sought to develop a mouse model of EV-D68 infection and determine the mechanisms underlying airway disease. BALB/c mice were inoculated...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Rajput, Charu, Han, Mingyuan, Bentley, J. Kelley, Lei, Jing, Ishikawa, Tomoko, Wu, Qian, Hinde, Joanna L., Callear, Amy P., Stillwell, Terri L., Jackson, William T., Martin, Emily T., Hershenson, Marc B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6141171/
https://ncbi.nlm.nih.gov/pubmed/30135310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.121882
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