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The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism
Adaptor proteins link surface receptors to intracellular signaling pathways, and potentially control the way cells respond to nutrient availability. Mice deficient in p66Shc, the most-recently evolved isoform of the Shc1 adaptor proteins and a mediator of receptor tyrosine kinase signaling display r...
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| 出版年: | Sci Signal |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260967/ https://ncbi.nlm.nih.gov/pubmed/24550542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2004785 |
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