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Defective FANCI Binding by a Fanconi Anemia-Related FANCD2 Mutant
FANCD2 is a product of one of the genes associated with Fanconi anemia (FA), a rare recessive disease characterized by bone marrow failure, skeletal malformations, developmental defects, and cancer predisposition. FANCD2 forms a complex with FANCI (ID complex) and is monoubiquitinated, which facilit...
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| Veröffentlicht in: | PLoS One |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260917/ https://ncbi.nlm.nih.gov/pubmed/25489943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114752 |
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