Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitate their clearance by human macrophages

Recently we reported the first known incidence of antibodies possessing catalytic sialidase activity (sialidase abzymes) in the serum of patients with multiple myeloma and systemic lupus erythematosus (SLE). These antibodies desialylate biomolecules, such as glycoproteins, gangliosides and red blood...

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Publicat a:Clin Exp Immunol
Autors principals: Tomin, A, Dumych, T, Tolstyak, Y, Kril, I, Mahorivska, I, Bila, E, Stoika, R, Herrmann, M, Kit, Y, Bilyy, R
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2015
Matèries:
Focus on Dying Autologous Cells as Instructors of the Immune System. Series Originators and Editors: Christian Berens and Martin Herrmann
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260892/
https://ncbi.nlm.nih.gov/pubmed/24580640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12312
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