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Sialidase of Glaesserella parasuis Augments Inflammatory Response via Desialylation and Abrogation of Negative Regulation of Siglec-5

Siglecs are sialic acid-binding immunoglobulin-like lectins that play an important role in tissue homeostasis, immune response, and pathogen infection. Bacterial sialidases act on natural ligands of Siglecs, interfering with the Siglec-mediated immune response. Glaesserella parasuis is a porcine bac...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Song, Yuping, Pan, Qicong, Xiao, Jing, Li, Wenjie, Ma, Hui, Chen, Huanchun, Cai, Xuwang, Xu, Xiaojuan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091100/
https://ncbi.nlm.nih.gov/pubmed/33526563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00696-20
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