Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitate their clearance by human macrophages

Recently we reported the first known incidence of antibodies possessing catalytic sialidase activity (sialidase abzymes) in the serum of patients with multiple myeloma and systemic lupus erythematosus (SLE). These antibodies desialylate biomolecules, such as glycoproteins, gangliosides and red blood...

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Bibliografski detalji
Izdano u:Clin Exp Immunol
Glavni autori: Tomin, A, Dumych, T, Tolstyak, Y, Kril, I, Mahorivska, I, Bila, E, Stoika, R, Herrmann, M, Kit, Y, Bilyy, R
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2015
Teme:
Focus on Dying Autologous Cells as Instructors of the Immune System. Series Originators and Editors: Christian Berens and Martin Herrmann
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260892/
https://ncbi.nlm.nih.gov/pubmed/24580640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12312
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