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ROS inhibit autophagy by downregulating ULK1 mediated by the phosphorylation of p53 in selenite-treated NB4 cells

Reactive oxygen species (ROS) have an important role in regulating various cellular processes. Our previous study confirmed that selenite, an anti-tumour agent, triggered apoptosis through the production of ROS in multiple types of cancer cells. In this study, we discovered that ROS also inhibited p...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Ci, Y, Shi, K, An, J, Yang, Y, Hui, K, Wu, P, Shi, L, Xu, C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260759/
https://ncbi.nlm.nih.gov/pubmed/25429619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.506
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