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Molecular and biochemical characterization of Mottled-dappled, an embryonic lethal Menkes disease mouse model

Mottled-dappled (Mo-dp) is a mouse model of Menkes disease caused by a large, previously uncharacterized deletion in the 5' region of Atp7a, the mouse ortholog of ATP7A. Affected mutants die in utero at embryonic day 17, and show bending and thickening of the ribs and distortion of the pectoral...

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Bibliografski detalji
Izdano u:Mol Genet Metab
Glavni autori: Haddad, Marie Reine, Patel, Keyur D., Sullivan, Patricia H., Goldstein, David S., Murphy, Kevin M., Centeno, Jose A., Kaler, Stephen G.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259894/
https://ncbi.nlm.nih.gov/pubmed/25456742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2014.10.001
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