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Molecular and biochemical characterization of Mottled-dappled, an embryonic lethal Menkes disease mouse model

Mottled-dappled (Mo-dp) is a mouse model of Menkes disease caused by a large, previously uncharacterized deletion in the 5' region of Atp7a, the mouse ortholog of ATP7A. Affected mutants die in utero at embryonic day 17, and show bending and thickening of the ribs and distortion of the pectoral...

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Dades bibliogràfiques
Publicat a:Mol Genet Metab
Autors principals: Haddad, Marie Reine, Patel, Keyur D., Sullivan, Patricia H., Goldstein, David S., Murphy, Kevin M., Centeno, Jose A., Kaler, Stephen G.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259894/
https://ncbi.nlm.nih.gov/pubmed/25456742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2014.10.001
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