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Molecular and biochemical characterization of Mottled-dappled, an embryonic lethal Menkes disease mouse model
Mottled-dappled (Mo-dp) is a mouse model of Menkes disease caused by a large, previously uncharacterized deletion in the 5' region of Atp7a, the mouse ortholog of ATP7A. Affected mutants die in utero at embryonic day 17, and show bending and thickening of the ribs and distortion of the pectoral...
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| Veröffentlicht in: | Mol Genet Metab |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4259894/ https://ncbi.nlm.nih.gov/pubmed/25456742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2014.10.001 |
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